AustralieFrV1, Main, Exploration, bibRecord, 005844

The Seville Expert Workshop for Progress in Posttransplant Lymphoproliferative Disorders

Identifieur interne : 005844 ( Main/Exploration ); précédent : 005843; suivant : 005845

The Seville Expert Workshop for Progress in Posttransplant Lymphoproliferative Disorders

Auteurs : Denis Glotz [France] ; Jeremy R. Chapman [Australie] ; Vikas R. Dharnidharka [États-Unis] ; Douglas W. Hanto [États-Unis] ; Maria C. R. Castro [Brésil] ; Hans H. Hirsch [Suisse] ; Véronique Leblond [France] ; Aneesh K. Mehta [États-Unis] ; Bruno Moulin [France] ; Antonio Pagliuca [Royaume-Uni] ; Julio Pascual [Espagne] ; Alan B. Rickinson [Royaume-Uni] ; Francesco P. Russo [Italie] ; Ralf U. Trappe [Allemagne] ; Angela C. Webster [Australie] ; Andreas O. Zuckermann [Autriche] ; Thomas G. Gross [États-Unis]

Source :

Transplantation [ 0041-1337 ] ; 2012.

RBID : Pascal:12-0423761

Descripteurs français

Pascal (Inist)
- Syndrome lymphoprolifératif posttransplantation, Expert, Atelier, Syndrome lymphoprolifératif, Greffe.

English descriptors

KwdEn :
- Expert, Graft, Lymphoproliferative syndrome, Posttransplant lymphoproliferative disorder, Workshop.

Abstract

Posttransplant lymphoproliferative disorders (PTLDs) are associated with significant morbidity and mortality among solid-organ transplant patients, but approaches to diagnosis and management vary considerably. An international multidisciplinary panel evaluated current understanding of risk factors and classification systems and developed recommendations to aid in PTLD prevention. We considered evidence on PTLD risk factors including Epstein-Barr virus serostatus and immunosuppression and identified knowledge gaps for future research. Recommendations address prophylactic and preemptive strategies to minimize PTLD development, including modulation of immunosuppression and antiviral drug regimens. Finally, new classification criteria were outlined that may help facilitate standardized reporting and improve our understanding of PTLD.

Affiliations:

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Le document en format XML

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<author><name sortKey="Mehta, Aneesh K" sort="Mehta, Aneesh K" uniqKey="Mehta A" first="Aneesh K." last="Mehta">Aneesh K. Mehta</name>
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<author><name sortKey="Moulin, Bruno" sort="Moulin, Bruno" uniqKey="Moulin B" first="Bruno" last="Moulin">Bruno Moulin</name>
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<author><name sortKey="Pagliuca, Antonio" sort="Pagliuca, Antonio" uniqKey="Pagliuca A" first="Antonio" last="Pagliuca">Antonio Pagliuca</name>
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<country>Royaume-Uni</country>
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<author><name sortKey="Pascual, Julio" sort="Pascual, Julio" uniqKey="Pascual J" first="Julio" last="Pascual">Julio Pascual</name>
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<s2>Barcelona</s2>
<s3>ESP</s3>
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<author><name sortKey="Rickinson, Alan B" sort="Rickinson, Alan B" uniqKey="Rickinson A" first="Alan B." last="Rickinson">Alan B. Rickinson</name>
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<author><name sortKey="Russo, Francesco P" sort="Russo, Francesco P" uniqKey="Russo F" first="Francesco P." last="Russo">Francesco P. Russo</name>
<affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Gastroenterology and Multivisceral Transplant Unit, Department of Surgical, Oncological and Gastroenterological Sciences, University Hospital of Padua</s1>
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<sZ>13 aut.</sZ>
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<author><name sortKey="Trappe, Ralf U" sort="Trappe, Ralf U" uniqKey="Trappe R" first="Ralf U." last="Trappe">Ralf U. Trappe</name>
<affiliation wicri:level="3"><inist:fA14 i1="14"><s1>Department of Internal Medicine II: Hematology and Oncology, University Medical Center Schleswig-Holstein</s1>
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<author><name sortKey="Webster, Angela C" sort="Webster, Angela C" uniqKey="Webster A" first="Angela C." last="Webster">Angela C. Webster</name>
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<country>Australie</country>
<wicri:noRegion>Westmead, New South Wales</wicri:noRegion>
<orgName type="university">Université de Sydney</orgName>
<placeName><settlement type="city">Sydney</settlement>
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</affiliation>
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<author><name sortKey="Zuckermann, Andreas O" sort="Zuckermann, Andreas O" uniqKey="Zuckermann A" first="Andreas O." last="Zuckermann">Andreas O. Zuckermann</name>
<affiliation wicri:level="3"><inist:fA14 i1="15"><s1>Department of Cardiac Surgery, Medical University of Vienna</s1>
<s2>Vienna</s2>
<s3>AUT</s3>
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<country>Autriche</country>
<placeName><settlement type="city">Vienne (Autriche)</settlement>
<region nuts="2" type="province">Vienne (Autriche)</region>
</placeName>
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</author>
<author><name sortKey="Gross, Thomas G" sort="Gross, Thomas G" uniqKey="Gross T" first="Thomas G." last="Gross">Thomas G. Gross</name>
<affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Division of Hematology/Oncology/BMT, Nationwide Children's Hospital</s1>
<s2>Columbus, OH</s2>
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<country>États-Unis</country>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">The Seville Expert Workshop for Progress in Posttransplant Lymphoproliferative Disorders</title>
<author><name sortKey="Glotz, Denis" sort="Glotz, Denis" uniqKey="Glotz D" first="Denis" last="Glotz">Denis Glotz</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Nephrology and Transplantation Service, Hopital Saint-Louis</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chapman, Jeremy R" sort="Chapman, Jeremy R" uniqKey="Chapman J" first="Jeremy R." last="Chapman">Jeremy R. Chapman</name>
<affiliation wicri:level="4"><inist:fA14 i1="02"><s1>Centre for Transplantation and Renal Research, University of Sydney, Westmead Hospital</s1>
<s2>Westmead, New South Wales</s2>
<s3>AUS</s3>
<sZ>2 aut.</sZ>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Westmead, New South Wales</wicri:noRegion>
<orgName type="university">Université de Sydney</orgName>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dharnidharka, Vikas R" sort="Dharnidharka, Vikas R" uniqKey="Dharnidharka V" first="Vikas R." last="Dharnidharka">Vikas R. Dharnidharka</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Division of Pediatric Nephrology, University of Florida and Shands Children's Hospital</s1>
<s2>Gainesville, FL</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Gainesville, FL</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hanto, Douglas W" sort="Hanto, Douglas W" uniqKey="Hanto D" first="Douglas W." last="Hanto">Douglas W. Hanto</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Harvard Medical School and Transplant Institute at Beth Israel Deaconess Medical Center</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Harvard Medical School and Transplant Institute at Beth Israel Deaconess Medical Center</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Castro, Maria C R" sort="Castro, Maria C R" uniqKey="Castro M" first="Maria C. R." last="Castro">Maria C. R. Castro</name>
<affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Kidney Transplantation Unit and Laboratory of Immunology, São Paulo University</s1>
<s2>São Paulo</s2>
<s3>BRA</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Brésil</country>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hirsch, Hans H" sort="Hirsch, Hans H" uniqKey="Hirsch H" first="Hans H." last="Hirsch">Hans H. Hirsch</name>
<affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Transplantation Virology, Department of Biomedicine, University of Basel and Division of Infectious Diseases, University Hospital Basel</s1>
<s2>Basel</s2>
<s3>CHE</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Suisse</country>
<wicri:noRegion>Basel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Leblond, Veronique" sort="Leblond, Veronique" uniqKey="Leblond V" first="Véronique" last="Leblond">Véronique Leblond</name>
<affiliation wicri:level="3"><inist:fA14 i1="07"><s1>UPMC Univ Paris 06, GRC N°11, GRECHY and AP-HP Department of Haematology, Pitie-Salpetriere Hospital</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mehta, Aneesh K" sort="Mehta, Aneesh K" uniqKey="Mehta A" first="Aneesh K." last="Mehta">Aneesh K. Mehta</name>
<affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Division of Infectious Diseases, Emory University School of Medicine</s1>
<s2>Atlanta, GA</s2>
<s3>USA</s3>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Atlanta, GA</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Moulin, Bruno" sort="Moulin, Bruno" uniqKey="Moulin B" first="Bruno" last="Moulin">Bruno Moulin</name>
<affiliation wicri:level="3"><inist:fA14 i1="09"><s1>Nephrology and Renal Transplantation Department, University Hospital of Strasbourg</s1>
<s2>Strasbourg</s2>
<s3>FRA</s3>
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</inist:fA14>
<country>France</country>
<placeName><region type="region">Grand Est</region>
<region type="old region">Alsace (région administrative)</region>
<settlement type="city">Strasbourg</settlement>
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</affiliation>
</author>
<author><name sortKey="Pagliuca, Antonio" sort="Pagliuca, Antonio" uniqKey="Pagliuca A" first="Antonio" last="Pagliuca">Antonio Pagliuca</name>
<affiliation wicri:level="3"><inist:fA14 i1="10"><s1>Department of Haematological Medicine, King's College Hospital</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pascual, Julio" sort="Pascual, Julio" uniqKey="Pascual J" first="Julio" last="Pascual">Julio Pascual</name>
<affiliation wicri:level="3"><inist:fA14 i1="11"><s1>Department of Nephrology, Hospital del Mar</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rickinson, Alan B" sort="Rickinson, Alan B" uniqKey="Rickinson A" first="Alan B." last="Rickinson">Alan B. Rickinson</name>
<affiliation wicri:level="4"><inist:fA14 i1="12"><s1>School of Cancer Sciences, University of Birmingham</s1>
<s2>Birmingham</s2>
<s3>GBR</s3>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Birmingham</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Midlands de l'Ouest</region>
<settlement type="city">Birmingham</settlement>
</placeName>
<orgName type="university">Université de Birmingham</orgName>
</affiliation>
</author>
<author><name sortKey="Russo, Francesco P" sort="Russo, Francesco P" uniqKey="Russo F" first="Francesco P." last="Russo">Francesco P. Russo</name>
<affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Gastroenterology and Multivisceral Transplant Unit, Department of Surgical, Oncological and Gastroenterological Sciences, University Hospital of Padua</s1>
<s2>Padua</s2>
<s3>ITA</s3>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<wicri:noRegion>Padua</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Trappe, Ralf U" sort="Trappe, Ralf U" uniqKey="Trappe R" first="Ralf U." last="Trappe">Ralf U. Trappe</name>
<affiliation wicri:level="3"><inist:fA14 i1="14"><s1>Department of Internal Medicine II: Hematology and Oncology, University Medical Center Schleswig-Holstein</s1>
<s2>Campus Kiel, Kiel</s2>
<s3>DEU</s3>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<placeName><region type="land" nuts="2">Schleswig-Holstein</region>
<settlement type="city">Kiel</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Webster, Angela C" sort="Webster, Angela C" uniqKey="Webster A" first="Angela C." last="Webster">Angela C. Webster</name>
<affiliation wicri:level="4"><inist:fA14 i1="02"><s1>Centre for Transplantation and Renal Research, University of Sydney, Westmead Hospital</s1>
<s2>Westmead, New South Wales</s2>
<s3>AUS</s3>
<sZ>2 aut.</sZ>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Westmead, New South Wales</wicri:noRegion>
<orgName type="university">Université de Sydney</orgName>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zuckermann, Andreas O" sort="Zuckermann, Andreas O" uniqKey="Zuckermann A" first="Andreas O." last="Zuckermann">Andreas O. Zuckermann</name>
<affiliation wicri:level="3"><inist:fA14 i1="15"><s1>Department of Cardiac Surgery, Medical University of Vienna</s1>
<s2>Vienna</s2>
<s3>AUT</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Autriche</country>
<placeName><settlement type="city">Vienne (Autriche)</settlement>
<region nuts="2" type="province">Vienne (Autriche)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gross, Thomas G" sort="Gross, Thomas G" uniqKey="Gross T" first="Thomas G." last="Gross">Thomas G. Gross</name>
<affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Division of Hematology/Oncology/BMT, Nationwide Children's Hospital</s1>
<s2>Columbus, OH</s2>
<s3>USA</s3>
<sZ>17 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Columbus, OH</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Transplantation</title>
<title level="j" type="abbreviated">Transplantation</title>
<idno type="ISSN">0041-1337</idno>
<imprint><date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Transplantation</title>
<title level="j" type="abbreviated">Transplantation</title>
<idno type="ISSN">0041-1337</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Expert</term>
<term>Graft</term>
<term>Lymphoproliferative syndrome</term>
<term>Posttransplant lymphoproliferative disorder</term>
<term>Workshop</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Syndrome lymphoprolifératif posttransplantation</term>
<term>Expert</term>
<term>Atelier</term>
<term>Syndrome lymphoprolifératif</term>
<term>Greffe</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Posttransplant lymphoproliferative disorders (PTLDs) are associated with significant morbidity and mortality among solid-organ transplant patients, but approaches to diagnosis and management vary considerably. An international multidisciplinary panel evaluated current understanding of risk factors and classification systems and developed recommendations to aid in PTLD prevention. We considered evidence on PTLD risk factors including Epstein-Barr virus serostatus and immunosuppression and identified knowledge gaps for future research. Recommendations address prophylactic and preemptive strategies to minimize PTLD development, including modulation of immunosuppression and antiviral drug regimens. Finally, new classification criteria were outlined that may help facilitate standardized reporting and improve our understanding of PTLD.</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
<li>Australie</li>
<li>Autriche</li>
<li>Brésil</li>
<li>Espagne</li>
<li>France</li>
<li>Italie</li>
<li>Royaume-Uni</li>
<li>Suisse</li>
<li>États-Unis</li>
</country>
<region><li>Alsace (région administrative)</li>
<li>Angleterre</li>
<li>Catalogne</li>
<li>Grand Est</li>
<li>Grand Londres</li>
<li>Midlands de l'Ouest</li>
<li>Nouvelle-Galles du Sud</li>
<li>Schleswig-Holstein</li>
<li>Vienne (Autriche)</li>
<li>État de São Paulo</li>
<li>Île-de-France</li>
</region>
<settlement><li>Barcelone</li>
<li>Birmingham</li>
<li>Kiel</li>
<li>Londres</li>
<li>Paris</li>
<li>Strasbourg</li>
<li>Sydney</li>
<li>São Paulo</li>
<li>Vienne (Autriche)</li>
</settlement>
<orgName><li>Université de Birmingham</li>
<li>Université de Sydney</li>
</orgName>
</list>
<tree><country name="France"><region name="Île-de-France"><name sortKey="Glotz, Denis" sort="Glotz, Denis" uniqKey="Glotz D" first="Denis" last="Glotz">Denis Glotz</name>
</region>
<name sortKey="Leblond, Veronique" sort="Leblond, Veronique" uniqKey="Leblond V" first="Véronique" last="Leblond">Véronique Leblond</name>
<name sortKey="Moulin, Bruno" sort="Moulin, Bruno" uniqKey="Moulin B" first="Bruno" last="Moulin">Bruno Moulin</name>
</country>
<country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Chapman, Jeremy R" sort="Chapman, Jeremy R" uniqKey="Chapman J" first="Jeremy R." last="Chapman">Jeremy R. Chapman</name>
</region>
<name sortKey="Webster, Angela C" sort="Webster, Angela C" uniqKey="Webster A" first="Angela C." last="Webster">Angela C. Webster</name>
</country>
<country name="États-Unis"><noRegion><name sortKey="Dharnidharka, Vikas R" sort="Dharnidharka, Vikas R" uniqKey="Dharnidharka V" first="Vikas R." last="Dharnidharka">Vikas R. Dharnidharka</name>
</noRegion>
<name sortKey="Gross, Thomas G" sort="Gross, Thomas G" uniqKey="Gross T" first="Thomas G." last="Gross">Thomas G. Gross</name>
<name sortKey="Hanto, Douglas W" sort="Hanto, Douglas W" uniqKey="Hanto D" first="Douglas W." last="Hanto">Douglas W. Hanto</name>
<name sortKey="Mehta, Aneesh K" sort="Mehta, Aneesh K" uniqKey="Mehta A" first="Aneesh K." last="Mehta">Aneesh K. Mehta</name>
</country>
<country name="Brésil"><region name="État de São Paulo"><name sortKey="Castro, Maria C R" sort="Castro, Maria C R" uniqKey="Castro M" first="Maria C. R." last="Castro">Maria C. R. Castro</name>
</region>
</country>
<country name="Suisse"><noRegion><name sortKey="Hirsch, Hans H" sort="Hirsch, Hans H" uniqKey="Hirsch H" first="Hans H." last="Hirsch">Hans H. Hirsch</name>
</noRegion>
</country>
<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Pagliuca, Antonio" sort="Pagliuca, Antonio" uniqKey="Pagliuca A" first="Antonio" last="Pagliuca">Antonio Pagliuca</name>
</region>
<name sortKey="Rickinson, Alan B" sort="Rickinson, Alan B" uniqKey="Rickinson A" first="Alan B." last="Rickinson">Alan B. Rickinson</name>
</country>
<country name="Espagne"><region name="Catalogne"><name sortKey="Pascual, Julio" sort="Pascual, Julio" uniqKey="Pascual J" first="Julio" last="Pascual">Julio Pascual</name>
</region>
</country>
<country name="Italie"><noRegion><name sortKey="Russo, Francesco P" sort="Russo, Francesco P" uniqKey="Russo F" first="Francesco P." last="Russo">Francesco P. Russo</name>
</noRegion>
</country>
<country name="Allemagne"><region name="Schleswig-Holstein"><name sortKey="Trappe, Ralf U" sort="Trappe, Ralf U" uniqKey="Trappe R" first="Ralf U." last="Trappe">Ralf U. Trappe</name>
</region>
</country>
<country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Zuckermann, Andreas O" sort="Zuckermann, Andreas O" uniqKey="Zuckermann A" first="Andreas O." last="Zuckermann">Andreas O. Zuckermann</name>
</region>
</country>
</tree>
</affiliations>
</record>

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The Seville Expert Workshop for Progress in Posttransplant Lymphoproliferative Disorders

The Seville Expert Workshop for Progress in Posttransplant Lymphoproliferative Disorders

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